Autres Références:

Structure and antitumour activity of fucoidan isolated from sporophyll of Korean brown seaweed Undaria pinnatifida

Andriy Synytsya  , Woo-Jung Kim  , Sung-Min Kim  , Radek Pohl  , Alla Synytsya  , František Kvasnicka  , Jana Copíková  , Yong Il Park ,*

Department of Carbohydrate Chemistry and Technology, Institute of Chemical Technology in Prague, Technická 5, 166 28 Prague 6, Czech Republic bDepartment of Analytical Chemistry, Institute of Chemical Technology in Prague, Technická 5, 166 28 Prague 6, Czech Republic cDepartment of Meat Technology and Preservation, Institute of Chemical Technology in Prague, Technická 5, 166 28 Prague 6, Czech Republic d Institute of Organic Chemistry and Biochemistry AS CR, Flemingovo sq. 2, 166 28 Prague 6, Czech Republic Department of Biotechnology, The Catholic University of Korea, Bucheon-si, Gyeonggi-do 420-743, Republic of Korea

Fucoidan Derived from Undaria pinnatifida Induces Apoptosis in Human Hepatocellular Carcinoma SMMC-7721 Cells via the ROS-Mediated Mitochondrial Pathway.

Yang L, Wang P, Wang H, Li Q, Teng H, Liu Z, Yang W, Hou L, Zou X.

Mar Drugs. 2013 Jun 10;11(6):1961-76. doi: 10.3390/md11061961.

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Select item 237378422.Fucoidan inhibits the growth of hepatocellular carcinoma independent of angiogenesis.

Zhu C, Cao R, Zhang SX, Man YN, Wu XZ.

Evid Based Complement Alternat Med. 2013;2013:692549. doi: 10.1155/2013/692549. Epub 2013 May 12.

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Select item 237036153.Major vault protein regulates class A scavenger receptor-mediated TNF-α synthesis and apoptosis in macrophages.

Ben J, Zhang Y, Zhou R, Zhang H, Zhu X, Li X, Zhang H, Li N, Zhou X, Bai H, Yang Q, Li D, Xu Y, Chen Q.

J Biol Chem. 2013 May 23. [Epub ahead of print]

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Select item 235306464.Fucoidan inhibited 4T1 mouse breast cancer cell growth in vivo and in vitro via downregulation of Wnt/β-catenin signaling.

Xue M, Ge Y, Zhang J, Liu Y, Wang Q, Hou L, Zheng Z.

Nutr Cancer. 2013;65(3):460-8. doi: 10.1080/01635581.2013.757628.

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Select item 234185395.Low molecular weight fucoidan against renal ischemia-reperfusion injury via inhibition of the MAPK signaling pathway.

Chen J, Wang W, Zhang Q, Li F, Lei T, Luo D, Zhou H, Yang B.

PLoS One. 2013;8(2):e56224. doi: 10.1371/journal.pone.0056224. Epub 2013 Feb 13.

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Select item 233919036.Induction of apoptosis by low-molecular-weight fucoidan through calcium- and caspase-dependent mitochondrial pathways in MDA-MB-231 breast cancer cells.

Zhang Z, Teruya K, Eto H, Shirahata S.

Biosci Biotechnol Biochem. 2013;77(2):235-42. Epub 2013 Feb 7.

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Select item 233372537.The effect of sulfated (1→3)-α-l-fucan from the brown alga Saccharina cichorioides Miyabe on resveratrol-induced apoptosis in colon carcinoma Cells.

Vishchuk OS, Ermakova SP, Zvyagintseva TN.

Mar Drugs. 2013 Jan 21;11(1):194-212. doi: 10.3390/md11010194.
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Select item 233033028.Fucoidan extract enhances the anti-cancer activity of chemotherapeutic agents in MDA-MB-231 and MCF-7 breast cancer cells.

Zhang Z, Teruya K, Yoshida T, Eto H, Shirahata S.

Mar Drugs. 2013 Jan 9;11(1):81-98. doi: 10.3390/md11010081.

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Select item 231416849.Fucoidan interferes with Porphyromonas gingivalis-induced aneurysm enlargement by decreasing neutrophil activation.

Alsac JM, Delbosc S, Rouer M, Journé C, Louedec L, Meilhac O, Michel JB.

J Vasc Surg. 2013 Mar;57(3):796-805. doi: 10.1016/j.jvs.2012.07.039. Epub 2012 Nov 8.
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Select item 2291627010.Anticancer properties and mechanisms of fucoidan on mouse breast cancer in vitro and in vivo.

Xue M, Ge Y, Zhang J, Wang Q, Hou L, Liu Y, Sun L, Li Q.
PLoS One. 2012;7(8):e43483. doi: 10.1371/journal.pone.0043483. Epub 2012 Aug 20.

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Select item 2287082011.Protective effect of fucoidan against acetaminophen-induced liver injury.

Hong SW, Lee HS, Jung KH, Lee H, Hong SS.

Arch Pharm Res. 2012 Jun;35(6):1099-105. doi: 10.1007/s12272-012-0618-5. Epub 2012 Jun 30.

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Select item 2279094012.Important role of β1-integrin in fucoidan-induced apoptosis via caspase-8 activation.

Yamasaki Y, Yamasaki M, Tachibana H, Yamada K.

Biosci Biotechnol Biochem. 2012;76(6):1163-8. Epub 2012 Jun 7.

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Select item 2251049213.Fucoidan extract derived from Undaria pinnatifida inhibits angiogenesis by human umbilical vein endothelial cells.

Liu F, Wang J, Chang AK, Liu B, Yang L, Li Q, Wang P, Zou X.

Phytomedicine. 2012 Jun 15;19(8-9):797-803. doi: 10.1016/j.phymed.2012.03.015. Epub 2012 Apr 15.

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Select item 2236324214.Fucose-containing sulfated polysaccharides from brown seaweeds inhibit proliferation of melanoma cells and induce apoptosis by activation of caspase-3 in vitro.
Ale MT, Maruyama H, Tamauchi H, Mikkelsen JD, Meyer AS.

Mar Drugs. 2011 Dec;9(12):2605-21. doi: 10.3390/md9122605. Epub 2011 Dec 13.
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Select item 2232680915.Cytoprotective effects of fucoidan, an algae-derived polysaccharide on 5-fluorouracil-treated dendritic cells.

Jeong BE, Ko EJ, Joo HG.

Food Chem Toxicol. 2012 May;50(5):1480-4. doi: 10.1016/j.fct.2012.01.034. Epub 2012 Feb 1.

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Select item 2230116016.Fucoidan, a sulfated polysaccharide from brown algae, improves cognitive impairment induced by infusion of Aβ peptide in rats.

Gao Y, Li C, Yin J, Shen J, Wang H, Wu Y, Jin H.

Environ Toxicol Pharmacol. 2012 Mar;33(2):304-11. doi: 10.1016/j.etap.2011.12.022. Epub 2011 Dec 27.

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Select item 2222244017.Neuroprotective effect of fucoidan on H2O2-induced apoptosis in PC12 cells via activation of PI3K/Akt pathway.

Gao Y, Dong C, Yin J, Shen J, Tian J, Li C.

Cell Mol Neurobiol. 2012 May;32(4):523-9. doi: 10.1007/s10571-011-9792-0. Epub 2012 Jan 6.

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Select item 2209657218.Fucoidan extract induces apoptosis in MCF-7 cells via a mechanism involving the ROS-dependent JNK activation and mitochondria-mediated pathways.
Zhang Z, Teruya K, Eto H, Shirahata S.

PLoS One. 2011;6(11):e27441. doi: 10.1371/journal.pone.0027441. Epub 2011 Nov 11.

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Select item 2187503419.An unfractionated fucoidan from Ascophyllum nodosum: extraction, characterization, and apoptotic effects in vitro.

Foley SA, Szegezdi E, Mulloy B, Samali A, Tuohy MG.

J Nat Prod. 2011 Sep 23;74(9):1851-61. doi: 10.1021/np200124m. Epub 2011 Aug 29. Erratum in: J Nat Prod. 2012 Sep 28;75(9):1674. Szegezdi, Eva [added]; Samali, Afshin [added].

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Select item 2187423020.Anti-tumor activity of fucoidan is mediated by nitric oxide released from macrophages.

Takeda K, Tomimori K, Kimura R, Ishikawa C, Nowling TK, Mori N.

Int J Oncol. 2012 Jan;40(1):251-60. doi: 10.3892/ijo.2011.1168. Epub 2011 Aug 18.

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“Seaweed extracted molecules for Cancer Prevention or Treatment: Fucoidans “,Chapter 10 by P.Déléris,H.Nazih,J.-M. Bard,
University of Nantes,France,of a Book by Joël FLEURENCE: Seaweed in Health and Disease Prevention .

The natural compound fucoidan from New Zealand Undaria pinnatifida synergizes with the ERBB inhibitor lapatinib enhancing melanoma growth inhibition

 Varsha Thakur Case Western Reserve University, Jun Lu Auckland University of TechnologyGiuseppe Roscilli· Takis

Barbara Bedogni· Case Western Reserve University School of Medicine,Luigi Aurisicchio · Takis,Manuela Cappelletti,Emiliano Pavoni Takis

W. Lindsey White Auckland University of Technology