Autres Références:

Therapies from Fucoidan; Multifunctional Marine Polymers ,

publié dans le journal des Médicaments de la Mer (Marine Drugs) par Jhelen Fitton · University of Tasmania

Fucoidan Extract Induces Apoptosis in MCF-7 Cells via a Mechanism Involving the ROS-Dependent JNK Activation and Mitochondria-Mediated Pathways
By Zhongyuan Zhang ,Kiichiro Teruya ,Sanetaka Shirahata,Kyuchu University,Fukuoka,Japan, Hiroshi Eto ,Daiichi  Sangyo Co., Ltd., Osaka, Japan


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Fucoidan inhibits the growth of hepatocellular carcinoma independent of angiogenesis.

Zhu C, Cao R, Zhang SX, Man YN, Wu XZ.

Evid Based Complement Alternat Med. 2013;2013:692549. doi: 10.1155/2013/692549. Epub 2013 May 12.

PMID:23737842[PubMed – in process] Free PMC ArticleRelated citations

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Major vault protein regulates class A scavenger receptor-mediated TNF-α synthesis and apoptosis in macrophages.

Ben J, Zhang Y, Zhou R, Zhang H, Zhu X, Li X, Zhang H, Li N, Zhou X, Bai H, Yang Q, Li D, Xu Y, Chen Q.

J Biol Chem. 2013 May 23. [Epub ahead of print]

PMID:23703615[PubMed – as supplied by publisher] Free ArticleRelated citations

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Fucoidan inhibited 4T1 mouse breast cancer cell growth in vivo and in vitro via downregulation of Wnt/β-catenin signaling.

Xue M, Ge Y, Zhang J, Liu Y, Wang Q, Hou L, Zheng Z.

Nutr Cancer. 2013;65(3):460-8. doi: 10.1080/01635581.2013.757628.

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Low molecular weight fucoidan against renal ischemia-reperfusion injury via inhibition of the MAPK signaling pathway.

Chen J, Wang W, Zhang Q, Li F, Lei T, Luo D, Zhou H, Yang B.

PLoS One. 2013;8(2):e56224. doi: 10.1371/journal.pone.0056224. Epub 2013 Feb 13.

PMID:23418539[PubMed – in process] Free PMC ArticleRelated citations

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Induction of apoptosis by low-molecular-weight fucoidan through calcium- and caspase-dependent mitochondrial pathways in MDA-MB-231 breast cancer cells.

Zhang Z, Teruya K, Eto H, Shirahata S.Biosci Biotechnol Biochem. 2013;77(2):235-42. Epub 2013 Feb 7.

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Cytoprotective effects of fucoidan, an algae-derived polysaccharide on 5-fluorouracil-treated dendritic cells.

Jeong BE, Ko EJ, Joo HG.

Food Chem Toxicol. 2012 May;50(5):1480-4. doi: 10.1016/j.fct.2012.01.034. Epub 2012 Feb 1.

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Fucoidan, a sulfated polysaccharide from brown algae, improves cognitive impairment induced by infusion of Aβ peptide in rats.

Gao Y, Li C, Yin J, Shen J, Wang H, Wu Y, Jin H.

Environ Toxicol Pharmacol. 2012 Mar;33(2):304-11. doi: 10.1016/j.etap.2011.12.022. Epub 2011 Dec 27.

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Neuroprotective effect of fucoidan on H2O2-induced apoptosis in PC12 cells via activation of PI3K/Akt pathway.

Gao Y, Dong C, Yin J, Shen J, Tian J, Li C.

Cell Mol Neurobiol. 2012 May;32(4):523-9. doi: 10.1007/s10571-011-9792-0. Epub 2012 Jan 6

Effects of Fucoidan on proliferation,AMP-activated protein kinase, and downstream metabolism and

cell cycle-associated molecules in poorly differenciated human hepatoma HLF cells.

By Takumi KAWAGUCHI, Masaka HAYAKAWA, Hironori KOGA and Takuji TORIMORA

Liver Cancer Division, Research Center for Innovative Cancer Therapy, Kurume University, Kurume,Japan